Study: Medical Marijuana Linked to Long-Term Pain and Quality-of-Life Improvements for Endometriosis Patients

Drawing on patient-reported outcomes from 63 individuals, the analysis tracked changes over 18 months. The study was conducted by researchers from Imperial College London, Cardiff and Vale University Health Board, St. George’s Hospital NHS Trust, and Kings College London. The researchers found consistent improvements across all pain-specific measures, with statistically significant gains recorded at every follow-up point. The study also noted improvements in overall health-related quality of life, sleep quality, and anxiety levels.

In measures such as the Brief Pain Inventory and pain-severity scales, minimal to substantial clinical improvements were observed, ranging from 0% to 37% depending on the category.

Although 16 participants reported a total of 62 adverse events, the study did not identify unexpected safety concerns.

As an observational study, the authors emphasized that it cannot determine causation, but the findings reinforce the need for controlled clinical trials to better evaluate how medical marijuana might help patients living with endometriosis-associated chronic pain.